四苯硼钠直接滴定法测定盐酸哌吡酮的含量

The Assay of Pirenzepine by Sodium Tetraphenylborate Direct Titration

我们曾报道了用酸性染料直接滴定法测定盐酸哌吡(艹卓)酮的含量,在滴定初始时,水相无色,氯仿层为黄色,滴到水相出现黄色时即为终点。由于下层氯仿层颜色的反衬。

Pirenzepine was determined by the sodium tetraphenylborate direct titration, using orange yellow-Ⅳ-methylidyne blue as indicator. The result was in good agreement with that obtained by the acid dye direct titration. The average recovery of pirenzepine was 99.90% (n=10), and a variation coefficient was below 0.3%.