黄芩“安胎”功效的古今要义探讨

Investigation on the Essence of Ancient and Modern "Tocolysis" Efficacy of Scutellaria baicalensis

目的:为深化黄芩"安胎"功效的科学内涵提供依据。方法:从历史沿革、古代中医药理论、现代药理学研究等方面,对古今黄芩的"安胎"功效进行对比,并分析产生古今差异的原因。结果:历代本草著作中很多都对黄芩的"安胎"功效有过记载。黄芩的"安胎"功效与其具有的性寒味苦的特性有关,常用于治疗由于热病导致的胎动不安,但应用时必须严格遵循中医基础理论,辨证施治。同时,经现代药理学研究发现,黄芩"安胎"作用还与其清热抗炎、抑制病毒复制、增强免疫和抑制子宫收缩等作用密切相关。黄芩的"安胎"功效的古今差异与其道地性的变迁、古今医者对"安胎"概念的理解存在一定差异和临床应用的变化有较大关联。结论:了解黄芩"安胎"功效的古今差异,可为其进一步研究和临床应用提供参考。

OBJECTIVE： To provide reference for deepening the scientific connotation of ＂tocolysis＂ efficacy of Scutellaria baicalensis. METHODS： The ancient and modem ＂tocolysis＂ efficacy of S. baicalensis were compared in respects of historical evolu- tion, ancient TCM theory and modem pharmacology; the reasons for the ancient and modem difference were inferred and analyzed. RESULTS： The ＂tocolysis＂ efficacy of S. baicalensis was recorded in many ancient herbal works. The ＂tocolysis＂ efficacy of S. ba- icalensis was associated with bitter taste and cold nature, but differentiation of symptoms and signs should be based on the basic theory of TCM. At the same time, The ＂tocolysis＂ efficacy of S. baicalensis was also accoiated with the effects of clearing heat and anti-inflammatory, inhibiting viral replication, enhancing immunity and inhibiting uterine contraction. The difference of ancient and modem ＂tocolysis＂ efficacy of S. baicalensis had a great relationship with changes in genuineness, the difference in understanding of the concept of ancient and modem ＂tocolysis＂ and changes in clinical application. CONCLUSIONS： It provides reference for further study and clinical application of S. baicalensis to understand the difference of ancient and modem ＂tocolysis＂ efficacy.