内置生物套技术治疗早泄的临床研究

Surgical Treatment for Primary Premature Ejaculation with Inner Condom Technique

目的探索一种应用脱细胞异体真皮的"内置生物套"技术,降低阴茎的敏感度,观察其对早泄患者的影响。方法通过确定适应证后,选择20例早泄患者。采用冠状沟切口,于白膜浅面分离腔穴,植入脱细胞异体真皮,埋没导引针牵引缝合固定近端,远端与深筋膜缝合固定。术后持续加压包扎。6周后可开始性生活。结果所有患者术后恢复顺利,平均随访时间6个月,未发现血肿、感染等并发症。术前平均射精潜伏期0.67min(0.18~1.1min);术后阴道内射精潜伏期为2.37min(0.82~8.4min,P<0.05)。结论内置生物套技术通过植入脱细胞异体真皮,在阴茎体的皮肤和海绵体之间形成一道人为的组织屏障。从本项临床研究观察来看,该手术损伤小,术后并发症少,是一项相对安全的外科操作,而且可以显著延长早泄患者的阴道内射精潜伏期时间。

Objective To explore a novel surgical treatment for primary premature ejaculation with an inner condom technique. Methods Twenty 20 cases of primary premature ejaculation were selected with established inclusion criteria. The inner condom technique was performed after fully discussion and informed consent. A 2cm incision was made 1.5cm proximal to the coronal sulcus, through which a sharp dissection was then carried out under the Buck＇s fascia. A sheet of acellular dermal matrix was transferred to the subcutaneous pocket and fixed with vicry sutures to form an inner condom. The penis was immobilized with elastic bandage for 7 days and sutures re- moved after 10 days. Results The post- operative recovery was uneventful. No wound problem or complications was recorded during a mean follow up of 6 months. The mean intravaginal ejaculation latency time was increased from O. 67min to 2.37min, which is statistically significant. Conclusion The inner condom technique may be a safe and easy surgical treatment for premature ejaculation patients. Fur- ther studies are mandatory to verify the efficacy of this new treatment.