松龄血脉康对轻度原发性高血压病人血压及糖脂代谢的影响

Effects of Songlingxuemaikang(SLXMK) on blood pressure level and glucolipid metabolism in patients with mild essential hypertension

目的研究松龄血脉康胶囊对轻度原发性高血压病人血压及糖脂代谢的影响。方法 90例轻度原发性高血压病人按照数字表2∶1随机分成2组:松龄血脉康组60例,给予松龄血脉康胶囊口服(500 mg/粒,每日3次,每次3粒);氯沙坦钾组30例,给予氯沙坦钾片口服(50 mg/片,每日1次,每次1片)。疗程均为12周。结果经过12周治疗后,两组病人的血压、糖代谢指标治疗方法与治疗时间无交互作用(P>0.05);松龄血脉康组病人的血脂明显改善,治疗方法与治疗时间有交互作用(P<0.05)。结论松龄血脉康能显著改善轻度原发性高血压病人的血脂浓度。

Objective To investigated the effects of Songlingxuemaikang （SLXMK） on blood pressure level and glucolipid metabolism in patients with mild essential hypertension. Methods We enrolled 90 patients with mild essential hypertension in Xuanwu Hospital from January 2016 to December 2016. To evaluate the effects of SLXMK, the 90 patients were randomly assigned at a 2：1 ratio into 2 groups：the SLXMK group （500 mg per capsule, 4 500 mg/d, n=60） and the losartan potassium group （50 mg per table, 50 mg/d, n=30）. The total study period was 12 weeks, and all patients maintained a stable diet and life-style during this period.Results After 12 weeks treatment, there was no interaction effect between the treatment methods of blood pressure level and glycometabolism parameters and duration （P〉0.05）. In the SLXMK group, plasma lipid levels significantly improved and there was interaction effect between the treatment methods and duration （P〈0.05）.Conclusion In conclusion, SLXMK could effectively improve plasma lipid levels in patients with mild essential hypertension.