手术联合I^(125)粒子术中植入在颅内肿瘤治疗中的应用

Application of surgery combined with intra-operative I^(125) particles implantation in treatment of intracranial tumor

目的探讨手术联合I125粒子术中植入对颅内肿瘤治疗的效果。方法回顾性分析沈阳军区总医院2015年1月至2016年11月确诊为颅内肿瘤并采用手术联合I125粒子术中植入治疗的25例患者的临床资料,观察该方法治疗的效果,并作出评价。结果所有患者术后随访6~18个月,肿瘤在短期内均无复发倾向,无明显不良反应。结论手术联合I125粒子术中植入将内放射治疗与手术治疗相结合,使患者术后免于接受外放射治疗的痛苦,对多种颅内肿瘤的短期复发有较好的抑制作用。

Objective To discuss the efficacy of surgery combined with intra-operative I125 particles implantation in treatment of in- tracranial tumor. Methods The data of 25 cases diagnosed with intracranial tumors in general hospital of Shenyang Military Region from Jan- uary 2015 to November 2016 were retrospectively analyzed. All patients received the combination of surgery and I125 particles intra-operative implantation. The therapeutic effect was observed and evaluated. Results All the patients were followed up for 6 to 18 months and there was no signs of recurrence or adverse reactions in the short term. Conclusion The combination of surgery and I125 particles intra-operative im- plantation could avoid the pain of postoperative radiotherapy and inhibit the short-term recurrence of multiple intracranial tumors.