官能团化香豆素并[4,3-d]吡唑并[3,4-b]吡啶衍生物的合成及其对锌离子的选择性识别

Synthesis of Functionalized Coumarino[4,3-d]pyrazolo[3,4-b]pyridine Derivatives and Their Selective Recognition for Zn^(2+)

在硫酸铜催化下,通过3-乙酰乙酰基香豆素与5-氨基吡唑的加成环化反应合成了一系列官能团化的香豆素并[4,3-d]吡唑并[3,4-b]吡啶衍生物3a^3h.合成得到的部分化合物具有很高的荧光量子产率.利用荧光光谱考察了其与Ag^+、Cr^(3+)、Co^(2+)、Cu^(2+)、Pb^(2+)、Sn^(4+)、Fe^(3+)、Zn^(2+)等金属离子的作用,结果表明化合物3a和3b对Zn^(2+)具有很好的选择性识别能力.

A series of functionalized coumarino[4,3-d]pyrazolo[3,4-b]pyridine derivatives 3a-3h were synthesized by the addition and cyclization of 3-acetoacetylcoumarin with 5-aminopyrazole catalyzed by Cu SO4. Some of the synthesized compounds had high fluorescence quantum yields. The properties of the compounds with cations such as Ag^＋, Cr^3＋, Co^2＋, Cu^2＋, Pb^2＋, Sn^4＋, Fe^3＋ and Zn^2＋ were examined by fluorescence spectroscopy. The results showed that compounds 3a and 3b have selective recognition for Zn^2＋.