肠道菌群与人体疾病关系的研究进展

Research progress on the relationship between gastrointestinal microbiota and human diseases

肠道菌群种类繁多,细菌总数达100万亿,各菌群之间及其与人体之间相互作用,对人体健康产生了巨大影响.近几年,肠道菌群与人体疾病的关系成为国内外研究的热点,众多研究表明,肠道微生物群在调节人体多个系统疾病（包括消化系统疾病,代谢性疾病,神经精神疾病,免疫相关性疾病和肿瘤）的风险中起重要作用.本文对肠道菌群与人体疾病的关系进行文献整理和分析,总结近5年国内外关于肠道菌群与人体疾病关系的研究进展,为人类相关疾病的诊治提供新的思路.

There are a wide variety of gastrointestinal microbiota, and the total number of bacteria reached 100 trillion. The flora interacts with the human body, and has a great impact on human health. In recent years, the relationship between intestinal flora and human diseases has become a hot research at home and abroad. Many studies have shown that intestinal microbiome plays an important role in modulating risk of multiple systemic diseases, including digestive system diseases, metabolic diseases, neuropsychiatric diseases, immune-related diseases and tumors.In this paper, the relationship between intestinal flora and human diseases was reviewed and summarized. The research progress on the relationship between gastrointestinal microbiota and human diseases in recent five years was summarized, which provided new ideas for the diagnosis and treatment of human diseases.