不同麻醉深度对老年肠癌手术患者应激反应的影响分析

Effect of Different Anesthetic Depth on Stress Response in Elderly Patients With Colorectal Cancer Surgery

目的分析不同麻醉深度对老年肠癌手术患者应激反应的影响。方法研究2015年1月—2017年4月老年肠癌手术患者120例,随机分为A组(麻醉深度D_0)、B(麻醉深度D_2)、C组(麻醉深度E1)。对比3组患者应激反应。结果 C组手术结束及术后1天的ACTH、ET-1显著低于A组、B组,差异有统计学意义(P<0.05)。在气腹后、手术结束时B组心率、平均动脉压与A组、C组对比,差异有统计学意义(P<0.05)。结论 D_2的麻醉深度可较好的抑制患者应激反应,保持血流动力学稳定。

Objective To analyze the influence of different anesthesia depth on stress reaction in elderly patients with colorectal cancer surgery. Methods From January 2015 to April 2017, 120 patients with colorectal cancer surgery were studied, they were randomly divided into A group （anesthesia depth Do）, B （anesthesia depth D2） and C group （anesthesia depth E1）. Stress responses were compared between the 3 groups. Results The ACTH and ET-1 at the end of operation and one day after operation in group C were significantly lower than those in group A and group B, the difference was statistically significant （P 〈 0.05）. At the end of pneumoperitoneum and at the end of operation, the heart rate and mean arterial pressure of B group were compared with those of group A and group C, the difference was statistically significant （P 〈 0.05）. Conclusion The anesthetic depth of D2 can inhibit the stress response and maintain the hemodynamic stability.