硫酸沙丁胺醇和茶碱缓释片治疗急性老年哮喘的疗效

Efficacy of Salbutamol Sulfate and Theophylline Sustained-release Tablets in the Treatment of Acute Senile Asthma

目的探索硫酸沙丁胺醇气雾剂吸入与茶碱缓释片治疗急性老年哮喘的疗效。方法选取2016年2月—2017年2月我院收治的100例急性老年哮喘患者作为研究对象,将其抽签化分组,每组各有50例,对照组和观察组分别采用硫酸沙丁胺醇治疗和硫酸沙丁胺醇气雾剂吸入联合茶碱缓释片治疗。结果观察组患者的PaCO_2(38.48±3.21)mm Hg、PaO_2(99.65±5.12)mm Hg、FEV_1/FVC(83.52±3.15)%、FEV_1(98.46±1.23)%、总有效率(98.00%)、哮喘持续时间(2.74±1.22)min/次、哮喘发作次数(1.23±0.57)次/周,均优于对照组,差异具有统计学意义(P<0.05)。结论对急性老年哮喘患者实施硫酸沙丁胺醇气雾剂吸入联合茶碱缓释片治疗,效果显著。

Objective To explore the effect of salbutamol sulfate aerosol inhalation and theophylline sustained-release tablets in the treatment of acute elderly patients with asthma. Methods 100 elderly patients with acute asthma from February 2016 to February 2017 were randomly divided into two groups： control group and observation group were treated with only salbutamol sulfate and the combination of salbutamol sulfate and theophylline sustained-release tablets respectively. Results The PaCO2 was （38.48±3.21） mmHg, PaO2 was （99.65±5.12） mmHg, FEV1 / FVC was （83.52±3.15）%, FEV1 was （98.46±1.23）%, total effective rate was 98.00%, asthma lasting time was （2.74±1.22） min / time, the number of asthma attack was （1.23±0.57） time/week in observation group, which were better than the control group （P 〈0.05）. Conclusion Salbutamol sulfate aerosol inhalation combined with theophylline sustained-release tablets is effective in elderly patients with acute asthma.