期刊文献+

利培酮治疗康复期精神分裂症的临床疗效及其对患者认知功能及情感功能障碍的影响 被引量:7

下载PDF
导出
摘要 目的探讨利培酮治疗康复期精神分裂症的临床疗效及其对患者认知功能与情感功能障碍的影响。方法选取资阳市安岳县康复医院2016年3月—2017年2月收治的康复期精神分裂症患者70例,均采用利培酮治疗2个月。比较患者治疗前及治疗后情感障碍与认知功能障碍(非连续错误次数、连续错误次数、正确反应次数、正确分类数、总测验次数),并比较患者治疗前后阴性与阳性症状量表(PANSS)评分。结果治疗后,患者非连续错误次数、连续错误次数、总测验次数少于治疗前,正确反应次数、正确分类数多于治疗前(P<0.05)。治疗后,患者阳性症状、阴性症状、一般精神病理PANSS评分及总分低于治疗前(P<0.05)。结论采用利培酮治疗康复期精神分裂症的效果确切,可有效改善患者的认知功能及情感功能障碍。
出处 《临床合理用药杂志》 2017年第27期86-87,共2页 Chinese Journal of Clinical Rational Drug Use
  • 相关文献

二级参考文献41

  • 1焦传安,吴本波,张自学,唐述龙,盛成东,李军,宋苏琪,孔晓艺,俞海云.联合应用利培酮和认知行为疗法治疗康复期精神分裂症的疗效观察[J].当代医药论丛,2014,12(12):238-239. 被引量:6
  • 2Meltzer H Y, McGurk S R. The effects of clozapine, risperidone. and olanzapine on cognitive function in schizophrenia[J]. Schizophr Bull, 1999,25 (2) 233-255.
  • 3Young J W, Powell S B. Risbrough Vet al. Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia[J]. Pharmacol Ther, 2009,122 (2) : 150-202.
  • 4Stip E. Cognition, schizophrenia and the effect of antipsycholics[J]. Encephale,2006,32(3 Pt 1) :341-350.
  • 5Jeffrey, Lieberman, Michael Phillips. et al. Atypical and conven tional antipsychotic drugs in treatment-naive first-episode schizophrenia: a 52-week randomized trial of clozapine vs chlorpromazine[J]. Neuropsychopharmacology, 2003,28:995-1003.
  • 6Mary P, Richard Goldberg, John J,et al. Repeatable battery for the assessment of neuropsychologieal status as a screening test in schizophrenia, II: convergent/discriminam validity and diagnostic group comparisons[J]. Am J Psychiatry, 1999,156 . 1951-1957.
  • 7Gold J M, Queern C, Iannone V N,et al. Repeatable battery for the assessment of neuropsyebological status as a screening test in schizophrenia I: sensitivity, reliability, and validity[J].Am J Psychiatry, 1999,156:1944-1950.
  • 8Christopher M, James M, John J. Test-retest stability of the repeatable battery for the assessment of neuropsychological status in schizophrenia[J].Am J Psychiatry, 2002,159 : 838-844.
  • 9Palmer B W,Dawes S E,Heaton R K. What do we know about neu- ropsychological aspects of schizophrenia [J ]. Neuropsychol Rev. 2009,19(3) :365-384.
  • 10Bralet M C,Navarre M,Eskenazi A M,et al. Interest of a new instrument to assess cognition in schizophrenia: The Brief Assessment of Cognition in Schizophrenia (BACS)[J].Encephale, 2008. 34(6) :557-562.

共引文献39

同被引文献57

引证文献7

二级引证文献25

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部