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外周静脉血气分析在糖尿病酮症酸中毒及终末期糖尿病肾脏疾病中的应用 被引量:3

Application of peripheral venous blood gas analysis in patients with diabetic ketoacidosis and end-stage diabetic kidney disease
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摘要 目的 评估糖尿病酮症酸中毒(DKA)和终末期糖尿病肾脏疾病(DKD)患者外周静脉血与动脉血pH值、HCO3-浓度的相关性.方法 对40例DKA患者和40例终末期DKD患者的动、静脉血标本行血气分析,比较其血pH值及HCO3-浓度并进行相关性分析.结果 DKA患者的动脉血pH和HCO3-分别为(7.09±0.13)和(7.76±3.03)mmol/L,静脉血pH和HCO3-分别为(7.05±0.14)和(9.63±2.90) mmol/L,动、静脉血pH值和HCO3-差值分别为(0.04±0.03)和(-1.87 ±0.36)mmoL/L.终末期DKD患者的动脉血pH和HCO3-分别为(7.11±0.10)和(8.20±2.75) mmol/L,静脉血pH和HCO;分别为(7.07 0.11)和(10.00±2.65) mmol/L,动、静脉血pH和HCO3-差值分别为(0.04 ±0.02)和(-1.80 ±0.40)mmoVL.DKA患者动静血pH值和HCO3-浓度(r=0.987和r=0.994,P<0.001)及终末期DKD患者动静血pH值和HCO3-浓度(r=0.982和r=0.989,P <0.001)均呈高度相关.结论 外周静脉血气可以用于评价DKA及终末期DKD患者的酸碱状态. Objective To assess correlation between venous and arterial pH values as well as HCO3-concentrations in acidotic patients with diabetic ketoacidosis(DKA) and end-stage diabetic kidney disease(DKD).Methods Arterial and venous blood samples from DKA patients (40 cases) and end-stage DKD patients(40 cases) were analyzed for measurements of blood gas and acid-base status.Results In DKA patients,Arterial pH and HCO3-were(7.09 ±0.13) and (7.76 ± 3.03) mmol/L while venous pH and HCO3-were (7.05 ± 0.14) and (9.63 ± 2.90)mmol/L.The differences between arterial and venouspH and HCO3-were (0.04 ±0.03) and (-1 87 ± 0.36) mmol/L.In end-stage DKD patients,Arterial pH and HCO3-were(7.11 ±0.10) and (8.20 ± 2.75)mmol/L while venous pH and HCO3-were (7.07 ± 0.11) and (10.00 ± 2.65) mmol/L.The differences between arterial and venous pH and HCO3-were (0.04 ± 0.02) and (-1.80 ± 0.40) mmol/L.Arterial and venous pH and HCO3-were highly correlated both in DKA group (r =0.987 and r =0.994 respectively,P 〈 0.001) and end-stage DKD group (r =0.982 and r =0.989 respectively,P 〈 0.001).Conclusion Gas analysis of venous blood sample can be used to evaluate the acid-base status in DKA and DKD patients.
作者 杨颖 高凌 Yang Ying Gao Ling(Department of Endocrinology, Xiangyang Central Hospital, Xiangyang 441021, China)
出处 《临床内科杂志》 CAS 2017年第8期532-534,共3页 Journal of Clinical Internal Medicine
关键词 糖尿病酮症酸中毒 糖尿病肾脏疾病 动脉血气 静脉血气 Diabetic ketoacidosis Diabetic kidney disease Arterial blood gas Venous blood gas
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