针刺治疗对癫痫间歇期脑电图背景的影响

EEG Background during Epileptic Intermission Influenced by Acupuncture Therapy

目的:观察针刺治疗对发作间期癫痫患者脑电图背景的影响。方法:将40例间歇期癫痫患者随机分为针刺组和单纯西药对照组,针刺组予脑电图引导头皮针配合体针治疗,单纯西药对照组不进行针刺,评估临床疗效,并通过脑电图及脑电地形图检测观察治疗前后α、β、θ、δ频段功率值的变化情况,从而评估治疗对脑电图背景的影响。结果:针刺组能明显降低发作间期癫痫患者致痫灶及周围脑区的α1、α2、β2、θ和δ频段的绝对功率(P<0.05),同时能增加健侧脑区的α1、α2绝对功率,降低健侧脑区β2、θ和δ的绝对功率(P<0.05),与单纯西药对照组比较差异均具有统计学意义(P<0.05)。结论:针刺治疗癫痫疗效确定,可能与其改善脑电功率谱、提高脑电基本频率,使脑电图背景渐趋稳定和顺应性相关。

Objective：To observe the changes of EEG background by the treatment of acupuncture for epilepsy patients during interictal stage.Methods：40 patients were randomly divided into the treatment group and the control group.The treatment group was given EEG-guided scalp acupuncture combined with body acupuncture.The control group was only treated with western medicine.Clinical curative effect was evaluated after the treatment,and the changes of absolute band power（ABP） of α,β,θ and δ were observed before and after treatment according to EEG and brain electrical activity mapping（BEAM）.Results：The acupuncture treatment group could significantly decreased the ABP of α1,α2,β2,θ,and δ in the focal zone and its surrounding areas（P〈0.05）;and it increased the ABP of α1,α2in uninjured brain regions and decreased the ABP of β2,θ and δ（P〈0.05）;there were statistically significant differences compared to the control group（P〈0.05）.Conclusion：Acupuncture has definite effect on treating epilepsy,which is possibly related to improving EEG power spectra and basic frequency,and stabilizes EEG background.