100例未成年人原发性高血压中医证型及其与危险因素的关系

Study on 100 juvenile cases of TCM syndrome types of essential hypertension and influencing risk factors

目的探讨未成年人高血压的中医证型分布情况及其与生化指标、脂联素、瘦素的关系,为未成年人高血压病因病机和高血压辨证的客观化提供可能依据。方法收集100例原发性未成年人高血压患者的临床资料进行辨证分型,检测其血清生化指标、脂联素、瘦素水平,运用统计学方法进行数据分析。结果各证型按所占比例排列为:阴虚阳亢证>痰湿壅盛证>肝火亢盛证,血清APN水平在各证型中分布为痰湿壅盛证<肝火亢盛证<阴虚阳亢证,leptin水平在各证型中分布为痰湿壅盛证>阴虚阳亢证>肝火亢盛证,且比较具有统计学意义(P<0.05)。结论未成年人高血压出现率最高的证型为阴虚阳亢证;痰湿壅盛证患者更易出现脂质代谢紊乱。

Objective To investigate the distribution of TCM syndrome types of essential hypertension and their relationship to biochemical indicators, ADPN and Leptin so that to supply a basis to research of the mechanism of EH disease in juveniles and the objectification of its TCM syndromes. Methods TCM syndrome types of 100 Juveniles EH patients were collected to detect their serum biochemical indicators ANP and Leptin by data analysis. Results TCM syndrome frequency were as followed according to their percentages： yin deficiency with yang hyperactivity〉 accumulation of phlegm-dampness〉 pattern of blazing liver fire; Serum APN level of patients was accumulation of phlegm-dampness 〈pattern of blazing liver fire〈yin deficiency with yang hyperactivity. Leptin level of patients was accumulation ofphlegm-dampness〉yin deficiency withyang hyperactivity〉pattern of blazing liver fire, the frequency has statistical significance （P〈0.05）. Conclusion The most prevalent TCM syndrome type was yin deficiency with yang hyperactivity in juveniles EH patients. The patients with accumulation of phlegm-dampness are easy to suffer from disorder of lipid metabolism.