连云港市2007—2012年胰腺癌发病特征及趋势

Epidemiological characteristics and trend of pancreatic cancer in Lianyungang city from 2007 to 2012

目的分析连云港市2007—2012年胰腺癌发病特征及趋势。方法根据连云港市肿瘤登记系统上报的数据,计算居民胰腺癌的发病率、中标率和年龄别发病率等指标。率的变化趋势以变化百分比(PC)和年度变化百分比(APC)等指标描述,以t检验进行回归分析。结果 2007—2012年连云港市胰腺癌年均发病率为4.70/10万,中标率为3.67/10万,世标率为4.93/10万,35~64岁截缩率为7.39/10万,0~74岁累计率为0.60%。2007—2012年胰腺癌标化发病率PC和APC分别为79.45%和14.50%,呈上升趋势(P<0.05);女性胰腺癌标化发病率PC和APC分别为120.71%和19.67%,呈上升趋势(P<0.05),男性胰腺癌标化发病率PC和APC分别为55.15%和10.92%。胰腺癌发病率随居民年龄增长而增加。城市和农村胰腺癌标化发病率PC分别为32.14%和70.13%,APC分别为7.08%和16.17%,均呈上升趋势(P值均<0.05)。结论连云港市胰腺癌发病呈增长趋势,应加强胰腺癌的预防与控制工作,继续疾病监测,以掌握疾病长期流行趋势。

Objective To describe the epidemiological characteristics and trend of pancreatic cancer in Lianyungang city from 2007 to 2012. Methods Based on data of Lianyungang cancer registry system, crude incidence, China standardized incidence and age-standardized incidence were calculated. Trends of above incidences were described by indicators such as percent change （PC）and annual percentage change（APC） ,t test was used for regression analysis. Results The annual average crude incidence of pancreatic cancer in Lianyungang city was 4.70/102 , the China and world standardized incidences were 3.67/10s and 4.93/ 10s , respectively. The truncated rate of 35-64 years was 7.39/105 and cumulative rate of 0-74 years was 0.60%. The PC and APC of standardized pancreatic cancer incidence from 2007 to 2012 in Lianyungang were 79.45 % and 14.50%, respectively , demonstrating ascending trend（P〈0.05）. The PC and APC of female standardized incidence were 120.71% and 19.67%, respectively ,demonstrating ascending trend （P〈 0.05）. The PC and APC of male standardized incidences were 55.15 % and 10. 92%, respectively. The incidence increased upon age. The PC of standardized incidences in rural and urban area were 32.14% and 70.13%, respectively, while the corresponding APC were 7.08% and 16.17%, both demonstrating ascending trend （all P〈0.05）. Conclusion Pancreatic cancer standardized incidence demonstrated ascending trend in Lianyungang city. Effective preventive measures together with continuous surveillance should be carried out to obtain the long-term trend.