摘要
综述晶型药物研究的效应、研究方法,并对晶型药物在兽药中的应用前景进行综合分析和讨论,以期为晶型兽药的研究和管理提供有价值的参考。药物晶型不仅影响药物稳定性和生产、制剂工艺的可操作性以及药物的溶解度、溶出速率,并进而影响药物的生物利用度和有效性。
In this review, we comprehensively analyze and discuss the effect, research methods and application of polymorphic study in veterinary drugs in order to provide meaningful reference for the research and management of polymorphic veterinary drugs. Drug polymorphism can affect not only stability, operability of production and preparation process, but also solubility and dissolution rate, which will further influence bioavailability and effectiveness of drugs. Therefore, the research about quality control and management of polymorphic drugs is one of the most important topic in veterinary drug fields.
出处
《中国兽药杂志》
北大核心
2017年第10期68-73,共6页
Chinese Journal of Veterinary Drug
基金
国家重点研发计划(2016y FD0501306)
关键词
晶型药物
兽药
多晶型
polymorphic drugs
veterinary drugs
polymorphism
