浙江省2005～2010年头颈部恶性肿瘤生存率分析

Analysis of Survival Rate of Patients with Head and Neck Cancer During 2005～2010 in Zhejiang Province

[目的]对浙江省2005~2010年以人群为基础的头颈部恶性肿瘤患者进行生存率分析,为人群头颈部恶性肿瘤的生存评价提供参考依据。[方法]对2005~2010年浙江省卫生监测区10484例头颈部恶性肿瘤患者的生存情况进行随访,随访时间截止至2012年12月31日,用SURV3.01软件计算观察生存率(OS)和相对生存率(RS)。[结果]5种主要头颈部恶性肿瘤分别为甲状腺癌、鼻咽癌、喉癌、颜面皮肤癌和口腔癌,占所有头颈部恶性肿瘤的84.35%,5年OS分别为91.40%、50.44%、42.38%、72.22%和46.33%,5年RS分别为94.90%、54.30%、58.41%、90.72%和53.68%。甲状腺癌、鼻咽癌、喉癌、颜面皮肤癌、口腔癌5年RS在男性分别为92.44%、54.71%、48.70%、91.52%和52.14%,女性分别为95.55%、53.39%、42.80%、89.60%和56.49%;城市分别为95.82%、59.57%、63.85%、94.68%和61.24%,农村分别为93.98%、51.44%、54.76%、88.79%和48.99%,城市高于农村。[结论]头颈部恶性肿瘤中甲状腺癌预后最好,喉咽癌预后最差。城市地区头颈部恶性肿瘤生存率高于农村地区,公共卫生资源应向农村地区倾斜。

[Purpose] To analyze the survival rate of head and neck cancer on the populationbased cancer registry during 2005~2010 in Zhejiang,in order to provide information for the prognosis assessment and the control of these disease. [Methods] The deadline of the last follow-up for survival statuses of 10484 cases was December 31 st,2012. Cumulative observed survival rate（OS）and relative survival rate（RS） were calculated using SURV3.01 software drawn up by Hakulinen.[Results] Thyroid gland,nasopharynx,larynx,facial skin and mouth were the top 5 sites of the head and neck cancer occurring. The 5-year OS of 5 main types of head and neck cancer were 91.40%,50.44%,42.38%,72.22%,46.33% and 5-year RS were 94.90%,54.30%,58.41%,90.72%,53.68%,respectively. The 5-year RS of 5 main types of head and neck cancer of males vs. females were 92.44% vs. 95.55%,54.71% vs. 53.39%,48.70% vs. 42.81%,91.52% vs. 89.60% and52.14% vs. 56.49%,respectively. The 5-year RS of 5 main types of head and neck cancer of urban vs.rural were 95.82% vs. 93.98%,59.57% vs. 51.44%,63.85% vs. 54.76%,94.68% vs. 88.79% and 61.24% vs. 48.99%,respectively. The 5-year RS was higher in urban than that in rural. [Conclusion]Thyroid cancer has best prognosis and hypopharyngeal cancer has lowest prognosis among all head and neck cancers. There is wide variation in head and neck cancer survival between urban and rural. Public health resources should be focused on rural areas.