临床药师对盆腔炎性疾病患者抗感染治疗的药学监护效果

Effect on Pharmaceutical Care for Patient with Pelvic Inflammatory Disease in Anti-infection Treatment by Clinical Pharmacists

目的:探讨临床药师对盆腔炎性疾病患者抗感染治疗的药学监护效果。方法:重庆医科大学附属大学城医院(以下简称"我院")于2016年1月起正式开展临床药师驻科随医师查房工作,并开展临床药学服务,比较干预前(2015年)和干预后(2016年)各24例盆腔炎性疾病患者抗感染治疗的效果。结果:干预后,单用药物未覆盖致病菌、联合用药未覆盖致病菌、由于初治方案不合理导致换药的病例数所占比例较干预前明显降低,差异均有统计学意义(P<0.05);干预前有33.33%(8例)的患者接受的初始抗感染治疗方案符合推荐,干预后升至75.00%(18例),干预前后的差异有统计学意义(P<0.05);干预后患者的住院时间较干预前明显缩短,差异有统计学意义(P<0.05)。结论:临床药师对盆腔炎性疾病抗感染方案进行干预,可提高治疗效果,缩短患者住院时间,促进临床合理用药。

OBJECTIVE： To probe into the pharmaceutical care effects on anti-infection treatment for patient with pelvic inflammatory disease by clinical pharmacists. METHODS： Affiliated University-Town Hospital of Chongqing Medical University（ hereinafter referred to as ＂our hospital＂） developed resident clinical pharmacists warding around followed with clinicians,and provided pharmaceutical care. Effects of anti-infection treatment in 24 patients with pelvic inflammatory disease were compared before intervention（ 2015） and after intervention（ 2016）. RESULTS：After intervention,single medication did not cover the causative pathogen,drug combination did not cover the causative pathogen; compared with before intervention,the number of cases with dressing change induced by irrational initial treatment regimen decreased significantly,with statistically significant difference（ P〈0. 05）. Before treatment,8 cases（ 33. 33%） with initial treatment regimen met the recommendations; after intervention,18 cases（ 75. 00%）met the recommendations,the difference was statistically significant before and after treatment（ P〈0. 05）. Compared with before intervention,the length of hospital was shorter after intervention,with statistically significant difference（ P〈0. 05）. CONCLUSIONS： The clinical pharmacists provide intervention for anti-infection treatment for patient with pelvic inflammatory disease can improve the treatment effects,shortened the length of hospital and promote the rational drug use in clinic.