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Ciz1-V蛋白在卵巢浆液性腺癌中的表达及临床意义 被引量：1

Expression and significance of Ciz1-V protein in ovarian serous adenocarcinoma
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摘要 目的探讨Ciz1-V蛋白在卵巢浆液性腺癌中的表达及临床意义。方法收集40例卵巢浆液性腺癌标本及27例非卵巢浆液性腺癌标本,采用免疫组化法检测Ciz1-V蛋白表达,分析其表达情况及与临床病理特征的关系。结果 Ciz1-V蛋白在卵巢浆液性腺癌标本中阳性表达例数少于非卵巢浆液性腺癌标本(P<0.01)。在卵巢浆液性腺癌标本中,Ciz1-V蛋白阳性表达与肿瘤分级和国际妇产科联盟(FIGO)分期有关(P<0.05)。结论 Ciz1-V蛋白在卵巢浆液性腺癌中呈现低表达,其表达情况与肿瘤分级和FIGO分期相关。 Objective To investigate the expression and clinical significance of Ciz1-V protein in ovarian serous adenocarcinoma.Methods The expression of Ciz1-V protein was detected by immunohistochemical staining in 40 samples of ovarian serous adenocarcinoma and 27 samples of nonovarian serous adenocarcinoma.The relationship of Ciz1-V protein expression and clinicopathological characteristics was analyzed.Results The cases with positive expression of Ciz1-V protein were less in ovarian serous adenocarcinoma than those in non-ovarian serous adenocarcinoma（P〈0.01）.The expression of Ciz1-V protein in ovarian serous adenocarcinoma was related with tumor grading and International Federation of Gynecology and Obstetrics（FIGO）staging（P〈0.05）.Conclusion The expression of Ciz1-V protein in ovarian serous adenocarcinoma is lower and is related to tumor grading and FIGO staging.
作者 凌玲 苏东明
机构地区 南京医科大学病理学系
出处 《江苏医药》 CAS 2017年第18期1299-1301,F0003,共4页 Jiangsu Medical Journal
关键词 卵巢浆液性腺癌 Ciz1-V蛋白 Ovarian serous adenocarcinom Cizl-V protein
分类号 R737 [医药卫生—肿瘤]
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江苏医药
2017年 第18期

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