狗牙根乙酸乙酯部位化学成分研究

Chemical Constituents of Ethyl Acetate Fraction from Cynodon dactylon

目的对狗牙根(Cynodon dactylon)全草的化学成分进行研究。方法采用各种柱色谱方法对狗牙根化学成分进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果从狗牙根体积分数95%乙醇提取物的乙酸乙酯萃取部位中分离得到14个化合物,分别鉴定为:香草醛(1)、牛蒡子苷元(2)、麦芽酚(3)、(+)-去氢催吐萝芙木醇(4)、(3R,6 R,7 E)-3-hydroxy-4,7-megastigmadien-9-one(5)、地芰普内酯(6)、浙贝素(7)、3-吲哚甲醛(8)、阿魏酸(9)、罗汉松脂素(10)、松脂素(11)、咖啡酸乙酯(12)、紫花络石苷元(13)和impecylenolide(14)。结论化合物1~14均为首次从狗牙根属植物中分离得到。

OBJECTIVE To isolate and identify the chemical constituents from Cynodon dactylon. METHODS The chemi- cal constituents of the alcohol extract of C. dactylon, were isolated and purified by various chromatography methods, and their structures were identified by physical and chemical properties and spectral data. RESULTS Fourteen compounds were isolated from C. dactylon and their structures were examined by physicochemical characteristics and spectral data and identified as vanillin （ 1 ）, arctigenin （ 2 ）, maltol （ 3 ）, （ ＋ ） -dehydrovomifoliol （ 4 ）, （ 3R, 6R, 7E） -3-hydroxy-4,7-megastigmadien-9-one （ 5 ）, （ - ） -loliolide （6） , zhebeiresinol （ 7 ） , 1-indole-3-carboxaldehyde （ 8 ） , ferulic acid （ 9 ） , matairesinol （ 10 ） , pinoresinol （11）, ethyl caffeate （12）, traxillagenin （13）,and impecylenolide （14）. CONCLUSION Compounds 1 -14 are isolated from C. dactylon for the first time.