生物活性肽的制备及分离纯化方法研究进展

Research progress in preparation and purification of bioactive peptides

目前,含有生物活性肽的功能性制剂越来越受关注。生物活性肽作为多种食物蛋白的水解产物,是当前功能食品和膳食补充剂等领域的研究热点。生物活性肽是指一类对机体的功能或状况具有积极作用,并可能最终影响人体健康的特殊蛋白质片段,具有免疫调节、抗菌、抗氧化、降血压、抗衰老、抗肿瘤等多种生物学功能。因具有安全性高、来源丰富、生理功效明显和易于消化吸收等优点,生物活性肽在功能性食品成分和配料领域具有广阔应用前景。本文重点综述了生物活性肽的制备及分离纯化方法,并对其发展前景进行了展望。

Currently,functional preparations containing bioactive peptides are gaining more and more attention. Bioactive peptides,as products of hydrolysis of diverse food proteins,are the focus of current research in the field of functional foods,dietary supplements and so on.Bioactive peptides are defined as a class of specific protein fragments that have positive health effects on the body＇s function or condition and may ultimately affect human health.Studies have shown that bioactive peptides have a variety of biological functions such as immunomodulatory,antibacterial,antioxidative,antihypertensive,anti-aging,antitumoral and so on,and play important roles in human health. Due to its advantages of high safety,rich source,obvious physiological effect and easy digestion and absorption and,bioactive peptides have shown significant promise as functional food ingredients.In this paper,the preparation and purification of bioactive peptides were focused on and the future prospect of bioactive peptides was disscussed.