山西医科大学第一医院胃肠动力药的药物利用分析

Analysis of Utilization of Gastrointestinal Prokinetic Agents in the First Hospital of Shanxi Medical University

目的:探讨山西医科大学第一医院胃肠动力药的临床使用情况和药物利用趋势,为治疗胃肠功能紊乱性疾病提供数据并为临床合理用药提供参考。方法:对该院2003-2015年13年来临床胃肠动力药的品种、规格、限定日剂量(DDD)、用药人次(DDDs)、限定日费用(DDC)、销售金额及同步性比值进行统计分析。结果:2003-2015年主要应用促胃肠动力药5种,甲氧氯普胺的DDDs和DDC13年来均为最小,曲美布汀的DDDs13年来为最大,曲美布汀的DDD%也为最大,其次是多潘立酮。结论:同步性比值基本在1附近,说明该院胃肠动力药的使用较为合理,各项数据表明此类药物应用正朝着高效、安全、经济、适宜方向发展。

Objective To discuss the clinical use status and trends of utilization of the gastrointestinal prokineticagents in the First Hospital of Shanxi Medical University so as to provide data for the treatment of gastrointestinaldisorders and provide references for clinical rational drug use. Methods： The type, specification, defined dailydoes （DDD）, defined daily does system （DDDs）, defined daily cost （DDC）, sales amount, and synchronizationratio of the gastrointestinal prokinetic agents which had been used in the hospital for thirteen years from 2003 to2015 were analyzed statistically. Results： There were 5 main types of gastrointestinal prokinetic agents whichhad been used from 2003 to 2015. The DDDs and DDC of Metoclopramide were the smallest in these thirteenyears. The DDDs and DDD% of Trimebutine were the largest, followed by Domperidone. Conclusion： Thesynchronization ratio was around 1, indicating that the use of the gastrointestinal prokinetic agents in the hospitalwas reasonable. All the data showed that the use of such drugs was effective, safe, economical and suitable.