两种肠道清洁剂对便秘患者的肠道准备效果及影响因素分析

Analysis of Bowel Preparation Effects and Influencing Factors of Two Kinds of Intestinal Cleanser for Patients with Constipation

目的:分析复方聚乙二醇(Polyethylene Glycol,PEG)电解质散和20%甘露醇对便秘患者肠道准备的效果及影响因素。方法:选取2015年9月~2016年12月结肠镜诊疗前口服肠道清洁剂进行肠道准备的便秘患者544例,按照口服肠道清洁剂的不同分为PEG组239例和20%甘露醇组305例。对两组的肠道准备效果进行分级,并对肠道准备无效的因素进行分析。结果:肠道准备总无效率为22.79%,其中PEG组无效率为24.27%,20%甘露醇组无效率为21.64%,两组的肠道准备效果相比较,差异无统计学意义,P>0.05;便秘病程、平时是否服用促动力药或缓泻剂、肠道准备期间活动情况是PEG组肠道准备无效的影响因素;便秘病程是20%甘露醇组肠道准备无效的影响因素。结论:便秘患者在进行肠道准备时,对其进行个体化处理,有助于提高肠道准备的质量和结肠镜诊疗的准确率。

Objective： To analysis the bowel preparation effects and influencing factors of two kinds of intestinal cleanser for patients with constipation. Methods： From September 2015 to December 2016, 544 cases of constipation patients took oral intestinal cleanser for bowel preparation before colonoscopy were divided into PEG group with 239 cases and 20% mannitol group with 305 cases, according to the different types of intestinal cleanser. Classified the bowel preparation effects of the two groups, and analyzed the influencing factors of bowel preparation. Results： The total intestinal preparation inefficiency was 22.79%, the PEG group＇s intestinal preparation inefficiency was 24.27%, while the 20% mannitol group＇s intestinal preparation inefficiency was 21.64%. Compared the bowel preparation effect of the two groups, the difference was not statistically significant, P〉0.05; constipation course, usually taking prokinetic drugs or laxative activities during bowel preparation were the invalid factors affecting the PEG group; while the constipation course was the invalid factors affecting the 20% mannitol group. Conclusion： In the bowel preparation of patients with constipation, the individualized treatment can help to improve the quality of bowel preparation and the accuracy of colonoscopy.