大肠癌证候及其现代生物医学内涵研究

TCM Syndromes(Zheng) of Colorectal Cancer and Its Biomedical Basis

大肠癌(Colorectal cancer,CRC)可以归属于多个中医病证,临床表现复杂,可以呈现多种证候。现代研究初步揭示大肠癌证候与病理、细胞类型、分期及预后有密切关系;手术、化疗等现代治疗对大肠癌的证候有一定的影响;现代中医同时对大肠癌湿热蕴结、瘀血内阻、脾气亏虚、气血两虚、肝肾阴虚等证候的生物医学内涵进行了广泛的研究。这些研究对大肠癌证候的客观化和规范化研究有积极的意义。

Colorectal cancer（CRC） belongs to multiple diseases of traditional Chinese medicine（TCM）. CRC can exhibit sophisticated clinical manifestations and various TCM syndromes（Zheng）. Modern studies have revealed that syndromes（Zheng） of CRC are related to pathological characteristics, cell types, staging and prognosis. Surgery, chemotherapy and other modern treatments can influence the manifestations of syndromes（Zheng） of CRC. Modern TCM doctors have extensively studied the biomedical basis of syndromes（Zheng） of CRC, including accumulation of damp-heat（Shi-ReYun-Jie）, blood stasis（Yu-Xue-Nei-Zu）, spleen（Pi） deficiency（Pi-Qi-Kui-Xu）, deficiency of qi and blood（Qi-XueLiang-Xu）, deficiency of yin of liver（Gan） and kidney（Shen）（Gan-Shen-Yin-Xu） and other syndromes（Zheng）. These investigations may contribute to the objective and standardization study of syndromes（Zheng） in CRC.