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胆道排石合剂对实验性胆结石形成的预防作用探讨 被引量:4

Observation on Effect of Mixture for Removing Calculus in Preventing Formation of Experimental Gallstones
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摘要 目的 :用洁霉素皮下注射诱发豚鼠胆囊结石的动物模型 ,观察中药制剂胆道排石合剂在实验性胆结石形成中的预防作用。方法 :实验组在注射洁霉素的同时 ,灌服胆道排石合剂 ;对照组则灌服生理盐水。结果 :实验组动物胆囊结石形成率为 2 0 % ,对照组动物胆囊结石形成率为 85 % ,经统计学处理 ,两组间有非常显著差异 (P<0 .0 1)。结论 ;胆道排石合剂有抑制实验性胆结石形成的作用。 Objective:The animal test model of gallstones had been made to observe the effect of traditional Chinese mixture for removing calculus in preventing formation of experimental gallstones.Methods:The Guinea pigs in the test had been injected with lincomyin and poured the mixture down the throat and in the control,poured normal saline.Results:The rate of gallstone formation in the test was 20%,while that in the control,85%.There are significant difference between two groups( P <0 01).Conclusion:The mixture for removing calculus can be applied to inhibit the formation of experimental gallstones. [
出处 《实用中医药杂志》 2002年第9期3-4,共2页 Journal of Practical Traditional Chinese Medicine
关键词 胆结石 胆道排石合剂 预防 动物模型 中药 gallstones mixture for removing culcalus prevention animal test model
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参考文献2

  • 1[1]Scott A. J. Lincomycin-induced Cholecystitis and gallstones in guinea-pigs. Gastroenterology, 1976(71): 814.
  • 2[2]Lee S. P. Further observations in Lincomycin-induced Cholelithiasis in guinea-pigs. The Journal of Pathology, 1980(131): 117.

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