磁共振ADC全容积直方图区分肺癌常见病理类型的价值

The Value of Histogram-based Apparent Diffusion Coefficient in Distinguishing Common Pathological Subtypes of Lung Cancer

目的探讨磁共振弥散加权成像(DWI)的表观弥散系数(ADC)全容积直方图对肺癌常见病理类型的鉴别诊断价值。方法回顾性分析经病理证实的肺癌35例,在磁共振工作站ADC图上绘制整个肿瘤病灶的感兴趣区,用软件得出整个肿瘤的全容积ADC直方图,获得整个肿瘤的平均ADC值(ADCmean),分别对常见肺癌病理类型进行统计学比较。结果经ADC全容积直方图分析,肺小细胞癌的ADCmean明显小于非小细胞癌,差别有统计学意义(P<0.001);鳞状细胞癌的ADCmean低于腺癌,差别有统计学意义(P<0.05)。结论ADC全容积直方图分析可以客观地提供肿瘤的整体信息,能区别肺癌常见病理类型之间的差异,对肺癌的诊断有潜在优势。

Objective To evaluate whether histogram analysis of apparent diffusion coefficient （ADC） values can be used to differentiate common pathological subtype ofhmg cancers. Met.hod, Thirty-five hmg cancer patients were retrospectively analyzed.ADC histogram was obtained from the entire minor volume. ADCmean were obtained in a MR work station through software. Results The ADCmean was significantly lower in small cell carcinomas than that in that non-small cell carcinomas. The ADCmean was significantly lower in squamous cell carcinomas than that in adenocarcinomas. Conclusion Histogram analysis of ADC values in lung cancers has potential for differentiating histologic subtypes, providing information about the entire tumor.