前舒安胶囊治疗Ⅲ型前列腺炎的临床研究

Clinical research of treating type Ⅲ prostatitis with Qianshu'an capsule

目的:探讨前舒安胶囊治疗Ⅲ型前列腺炎的临床疗效。方法:试验采用自身对照试验,共纳入73例受试者,治疗周期共4周,分别于治疗前、治疗后第2周、治疗后第4周进行NIH-CPSI评分及前列腺按摩液ESP中白细胞计数,并评估疗效。结果:纳入试验病例共71例,4周治疗后,治愈5例(7.0%)显效23例(32.4%),有效32例(45.1%),无效11例(15.5%),总有效率为84.5%;治疗第2周、第4周NIHCPSI评分比较治疗前NIH-CPSI总评分、排尿质量评分、生活质量评分均有显著统计学差异(P<0.01);治疗第2周、第4周与治疗前相比,EPS中WBC计数均有统计学差异(P<0.05)。治疗期间未观察到不良反应事件。结论:采用前舒安胶囊治疗Ⅲ型前列腺炎疗效确切,安全性高,能够显著改善患者疼痛症状,提高生活质量。

Objectives： To investigate the clinical curative effect of Qianshu＇an capsule in treating type Ⅲprostatitis. Methods： The NIH-CPSI score and the WBC count in the prostate massage fluid ESP were measured before treatment,at 2 weeks after treatment and at 4 weeks after the treatment among the 73 subjects treated in theself-controlled trials. The efficacy was evaluated. Results： At 4 weeks after the treatment,there were 5 cases（7. 0%） cured,23 cases（32. 4%） remarkably effective,32 cases（45. 1%） effective and 11 cases（15. 5%） ineffective,a total effective rate of 84. 5%. Differences in the NIH-CPSI score,the voiding quality score and the quality of life score of NIH-CPSI between before and 2 weeks and 4 weeks after treatment were significantly different（ P 0. 01）. Difference in the WBC count in EPS was significantly different between before and 2 weeks and 4 weeks after treatment（ P 0. 05）. No adverse events were observed during treatment. Conclusion： Qianshu＇an capsule is effective and safe in treating patients with type Ⅲ prostatitis,which can significantly improve the pain symptoms and improve the quality of life.