单通道微创经皮肾镜取石术治疗复杂性肾结石的疗效及其对性功能影响分析

Effect of single channel minimally invasive percutaneous nephrolithotomy in the treatment of complex renal calculi and its effect on sexual function

目的:探讨单通道微创经皮肾镜取石术治疗复杂性肾结石患者的临床疗效及其对性功能影响。方法:选取2014年4月至2016年3月于我院接受治疗的复杂性肾结石患者共140例,随机分为常规组和观察组,每组各70例。常规组患者接受传统的开放性手术治疗,观察组患者接受通道微创经皮肾镜取石术(minimally invasive percutaneous nephrolithotomy,MPCNL)治疗,对比分析两组患者的临床治疗效果以及手术对患者性功能的影响。结果:观察组患者的手术时间、住院时间、术中出血量均明显低于常规组患者(P<0.05);观察组患者术后感染和血尿的发生率明显低于常规组患者(P<0.05);而两组患者内脏损害的发生率相比无明显统计学差异(P>0.05);随访6个月,观察组患者的勃起功能,对性生活的满意度以及性功能质量评分均明显高于常规组患者(P<0.05)。结论:与传统开放性手术相比,单通道微创经皮肾镜取石术治疗复杂性肾结石患者的临床疗效显著,减少术中出血量以及术后并发症发生率,提高患者性功能及性生活质量,值得临床推广应用。

Objectives： To investigate the effect of single channel minimally invasive percutaneous nephrolithotomy in the treatment of complex renal calculi and its effect on sexual function. Methods： A total of 140 patients with complicated renal calculi who were treated in our hospital from April 2014 to March 2016 were randomly divided into two groups： conventional group and observation group. Patients in conventional group received traditional open surgery. The patients in observation group received minimally invasive percutaneous nephrolithotomy（ MPCNL）. The clinical effect of surgery and effect on the sexual function of two groups were compared. Results： The operative time,hospital stay and intraoperative blood loss in observation group were significantly lower than these in conventional group（ P 0. 05）. The incidence of postoperative infection and hematuria in the observation group were significantly lower than these in the conventional group（ P 0. 05）. There was no significant difference in the incidence of visceral injury between two groups（ P 0. 05）. After 6 months＇ follow-up,the erectile function,sexual satisfaction and sexual function quality score in observation group were significantly higher than these in conventional group（ P 0. 05）. Conclusion： Compared with traditional open surgery,single-channel minimally invasive percutaneous nephrolithotomy for the treatment of patients with complex renal calculi has a significant clinical effect,and it can reduce the amount of intraoperative blood loss and the incidence of postoperative complications,and improve the quality of sexual life of patients,which is worth of application.