纳米炭混悬注射液作为SLN示踪剂对早期宫颈癌盆腔淋巴结转移状态预测价值分析

Predictive value of nanometer carbon suspension injection as SLN tracer in predicting pelvic lymph node metastasis of early cervical carcinoma

目的:分析纳米炭混悬注射液作为SLN示踪剂对早期宫颈癌盆腔淋巴结转移状态预测价值。方法:选取我院2015年2月至2015年12月妇科门诊及住院部确诊为浸润性宫颈癌的患者42例。注射纳米炭混悬注射液作为SLN示踪剂,切除黑染淋巴结。然后所有患者均进行广泛子宫切除术和腹腔镜盆腔淋巴结清扫术,标本送往实验室进行病理检验。结果:42例患者中40例检出SLN出现黑染,其中30例双侧均出现黑染。共清除出1004枚盆腔淋巴结,平均每例患者共切除23.9个淋巴结,每例患者平均SLN检验出的淋巴结为3.9。病理结果表明SLN准确率为100%,而假阴性为0%。结论:SLN被检测出来的淋巴引流区最多的是闭孔,其与盆腔淋巴结的转移具有一致性,且初步证明了纳米炭混悬液作为SLN示踪剂检测宫颈癌的安全性和可靠性。

Objectives： To analyze the predictive value of nanometer carbon suspension injection as SLN tracer in predicting pelvic lymph node metastasis of early cervical carcinoma. Methods： 42 patients with invasive cervical cancer in our hospital from February 2015 to December 2015 were selected. The carbon nanoparticles suspension injection was as SLN tracer. The black lymph node was resected. All patients received laparoscopic hysterectomy and pelvic lymph node dissection. The specimens were sent to the laboratory for pathological examination.Results： Among the 42 patients,there were 40 cases of SLN black staining and 30 cases of bilateral black staining.1004 pelvic lymph nodes were resected. The average number of lymph nodes resected was 23. 9 per patient. The average number of lymph node tested by SLN was 3. 9. Pathological results showed that the SLN accuracy rate was100%,and the false negative was 0%. Conclusion： SLN detected in the lymphatic drainage area is mostly closed.SLN is consistent with lymph node metastasis,which initially proves the safety and reliability of carbon nanoparticles suspension as SLN tracer in the detection of cervical cancer.