替吉奥胶囊联合顺铂治疗晚期胃癌24例临床分析

Clinical Analysis of Gimeracil and Oteracil Porassium Capsules and Cis-platinum in Treatment of 24 Cases with Advanced Gastric Cancer

目的研究替吉奥胶囊联合顺铂治疗晚期胃癌疾病的效果。方法该次研究对象选取时间于2014年12月—2016年12月在黑龙江省农垦红兴隆管理局中心医院肿瘤内科就医的晚期胃癌患者(48例),通过动态化随机单双号分组的方法将其分为2组(对照组:24例;观察组:24例),分别给予氟尿嘧啶联合顺铂、替吉奥胶囊联合顺铂治疗,分析2组患者的治疗效果以及不良反应发生率的差异性。结果观察组患者的治疗效果(20例)明显优于对照组患者(10例),不良反应发生率(6例)明显低于对照组患者(14例),差异有统计学意义(P<0.05)。结论替吉奥胶囊联合顺铂治疗晚期胃癌具有一定的应用效果。

Objective To research the effect of gimeracil and oteracil porassium capsules and cis-platinum in treatment of advanced gastric cancer. Methods 48 cases of patients with advanced gastric cancer treated in our hospital from December 2014 to December 2016 were selected and dynamically randomly divided into two groups with 24 cases in each, the control group and the observation group were respectively treated with fluorouracil and cis-platinum and gimeracil and oteracil porassium capsules and cis-platinum, and the differences in the treatment effect and incidence rate of adverse reactions were compared between the two groups. Results The treat-ment effect in the observation group was obviously better than that in the control group（20 cases vs 10 cases）, and the incidence rate of adverse reactions was obviously lower than that in the control group（6 cases vs 14 cases） and the difference was statistically signifi-cant（P 0.05）. Conclusion The gimeracil and oteracil porassium capsules and cis-platinum in treatment of advanced gastric cancer has a certain application effect.