SP ECT和SP ECT/CT肺通气/灌注显像

V/Q scanning using SPECT and SPECT/CT

肺通气/灌注（V/Q）平面显像常用于肺栓塞检查,但存在局限性,SPECT显像通过生成的三维显像数据可克服诸多局限.肺V/Q SPECT显像较平面显像有更高的灵敏度、特异性和准确性,且诊断不明确率低.SPECT显像可采用V/Q比值参数图显示和分析数据.较之CT肺血管造影,SPECT显像灵敏度高、辐射剂量低,且无造影剂相关的不良反应.任何配置有现代多模态显像设备的核医学科都可进行肺V/Q SPECT与CT（低剂量程序）融合显像,以提高诊断准确性.肺V/Q SPECT显像（有或无CT融合）也可应用于其他肺疾病诊断及研究.

Planar ventilation–perfusion (V/Q) scanning is often used to investigate pulmonary embolism; however, it has well-recognizedlimitations. SPECT overcomes many of these through its ability to generate 3-dimensional imaging data. V/Q SPECT has highersensitivity, specificity, and accuracy than planar imaging and a lower indeterminate rate. SPECT allows for new ways to displayand analyze data, such as parametric V/Q ratio images. Compared with CT pulmonary angiography, SPECT has higher sensitivity,a lower radiation dose, fewer technically suboptimal studies, and no contrast-related complications. Any nuclear medicinedepartment equipped with a modern hybrid scanner can now perform combined V/Q SPECT with CT (using low-dose protocols) tofurther enhance diagnostic accuracy. V/Q SPECT (with or without CT) has application in other pulmonary conditions and in research.