围生期孕产妇发生下肢深静脉血栓危险因素的病例对照研究

A Case Control Investigation of Risk Factors of Deep Venous Thrombosis in Perinatal Pregnant Women

目的探讨围生期孕产妇发生下肢深静脉血栓(DVT)的危险因素。方法选取2006年1月-2016年12月我院收治的46例并发DVT的围生期孕产妇(观察组)及同期50例未发生DVT的围生期孕产妇(对照组)作为研究对象,采用系统性回顾法分析所有患者的临床资料,分析比较2组患者孕产次数、分娩方式等各项临床资料及检查指标之间的差异。结果非条件多因素Logistic回归模型分析可得,分娩方式(剖宫产)、产后出血(有)、产褥期卧床时间(>72 h)及高血压(有)为围生期孕产妇DVT形成的独立危险因素(P<0.05)。结论临床应针对围生期孕产妇DVT形成的危险因素采取相应措施,避免该病发生。

Objective To investigate the risk factors of deep venous thrombosis（ DVT） in perinatal pregnant women.Methods Forty-six perinatal pregnant women（ observation group） with concurrent DVT and fifty cases of perinatal pregnant women（ control group） without DVT admitted to our hospital between January 2006 and December 2016 were selected as subjectes.The clinical data of all the patients was analyzed by systematic review,and the difference of the clinical data and the inspection indexes was analyzed and compared between the two groups. Results The mode of delivery（ cesarean section）,postpartum hemorrhage,bed time puerperium（ 72 h） and hypertension were independent risk factors for perinatal DVT（ P〈0.05） according to the multi-factor non-conditional logistic regression model analysis.Conclusion Clinicians should take measures against the risk factors of DVT in pregnant women in order to prevent DVT.