不换金正气散加减治疗小儿脾失健运型口臭症疗效观察

Clinical Effect of Modified Buhuangjin Zhengqi Powder in Treatment of Children with Fetid BreathDue to Dysfunction of the Spleen in Transportation

目的观察不换金正气散加减治疗小儿脾失健运型口臭症的临床疗效。方法将60例脾失健运型口臭症患儿随机分为治疗组与对照组,每组30例,治疗组予不换金正气散加减治疗,对照组予双歧杆菌四联活菌片治疗。结果治疗组临床疗效明显优于对照组(P<0.05)。在改善口臭、舌苔厚度、腹痛、嗳气、恶心呕吐、大便异常方面,治疗组优于对照组(P<0.05)。两组治疗后主症积分、次症积分、症状总积分均较治疗前明显降低(P<0.05),治疗组治疗后主症积分、次症积分、症状总积分下降值大于对照组(P<0.05)。结论不换金正气散加减治疗小儿口臭症脾失健运证疗效确切。

Objective To investigate the clinical effect of modified Buhuanjin Zhengqi Powder in the treatment of children with fetid breath due to dysfunction of the spleen in transportation.Methods A total of 60 children with fetid breath due to dysfunction of the spleen in transportationwere randomly divided into treatment group and control group,with 30 children in each group.The children in the treatment group were treated with modified Buhuanjin Zhengqi Powder,and those in the control group were given Bifidobacterium tetravaccine Tablets(live).Results The treatment group had a significantly better clinical outcome than the control group(P<0.05).Compared with the control group,the treatment group had significantly better improvements in fetid breath,thickness of the coating on the tongue,abdominal pain,belching,nausea/vomiting,and stool abnormalities(P<0.05).Both groups had significant reductions in primary symptom score,secondary symptom score,and total symptom score after treatment(P<0.05),and the treatment group had significantly greater reductions than the control group(P<0.05).Conclusion Modified Buhuanjin Zhengqi Powder has a marked clinical effect in the treatment of children with fetid breathdue to dysfunction of the spleen in transportation.