小儿肺炎合并胃食管反流发生现况及其影响因素调查

Prevalence and influencing factors of gastroesophageal reflux in children with pneumonia

目的探讨小儿肺炎合并胃食管反流发生现况及其影响因素。方法采用自行设计的调查量表收集468例小儿肺炎患儿一般人口学资料、合并胃食管反流发生情况、用药情况等,采用Logisitic回归分析小儿肺炎合并胃食管反流发生的影响因素。结果在我院儿科就诊的肺炎患儿468例,其中肺炎合并胃食管反流271例,发生率为57.9%;单因素分析结果显示:年龄、病情严重程度、慢性咽炎、营养不良、镇静药物使用、糖皮质激素是影响小儿肺炎合并胃食管反流发生的因素(P<0.05),性别、体重与小儿肺炎合并胃食管反流发生无关(P>0.05);Logisitic回归分析结果显示:年龄(OR=2.14)、病情严重程度(OR=3.54)、慢性咽炎(OR=2.61)、镇静药物使用(OR=3.42)、糖皮质激素使用(OR=2.31)是影响小儿肺炎合并胃食管反流发生的危险因素(P<0.05)。结论小儿肺炎合并胃食管反流发生率较高,年龄小、病情严重程度、有慢性咽炎、使用镇静药物和糖皮质激素使用是影响小儿肺炎合并胃食管反流发生的危险因素。

Objective To investigate the incidence and influencing factors of gastroesophageal reflux in chil-dren with pneumonia. Methods It used self-designed questionnaire to collect 468 cases of children with pneumonia in general demographic data, the incidence of gastroesophageal reflux, drug use, etc. It usedLogisitic regression to analyze the factors influencing the occurrence of gastroesophageal reflux in children with pneumonia. Results A total of 468 children with pneumonia were treated in our hospital. Among them, there were a total of 271 cases of pneumo-nia complicated with gastroesophageal reflux, and the incidence was about 57. 9%. The results of univariate analysis showed that age, the severity of the disease, chronic pharyngitis, malnutrition, the use of sedative drugs and glu-cocorticoid affected in children with pneumonia and gastroesophageal reflux （ P〈0. 05 ） . Sex and body weight were not associated with the incidence of gastroesophageal reflux in children with pneumonia （P〉0. 05）. Logisitic regres-sion analysis showed that age （OR=2. 14） and the severity of chronic pharyngitis （OR=3. 54）, （OR=2. 61）, the use of sedative drugs （ OR=3. 42 ） and glucocorticoid （ OR=2. 31 ） were the risk factors of pneumonia in children with gastroesophageal reflux （ P〈0. 05 ） . Conclusion Children with pneumonia complicated with gastroesophageal reflux have high incidence, and the risk factors include age, the severity of the disease, chronic pharyngitis, use of sedative drugs and glucocorticoid use.