埃索美拉唑钠的NMR研究

NMR Structural Elucidation of Esomeprazole Sodium

对埃索美拉唑钠在D_2O和DMSO溶液中的~1H和^(13)C NMR分别进行了检测,通过DEPT、~1H-~1H COSY、^(13)C-~1H HSQC、^(13)C-~1H HMBC等2D NMR技术对该化合物所有的~1H、^(13)C谱的信号进行了全归属.

In this study, esomeprazole sodium in D20 and DMSO solution in !H and 13 C NMR respectively were detected the 1H and 13C NMR chemical shifts of this compound were completely assigned using 2D NMR techniques, including DEPT、1H-1H C0SY、13C -1H HSQC、13C -1H HMBC.