内镜联合奥曲肽治疗上消化道出血的临床观察

Clinical observation ofendoscopy combination with octreotide treating upper gastrointestinal bleeding

目的探讨内镜钛夹联合奥曲肽治疗上消化道出血的临床效果。方法将2010年3月~2014年6月我院收治诊断为上消化道出血患者94例,随机分为A、B、C 3组,A组26例采用内镜止血治疗,B组45例采用内镜止血+奥曲肽治疗,C组23例单用奥曲肽治疗,比较3组患者治疗后72h的止血有效率。结果内镜止血+奥曲肽治疗的B组在上消化道出血72h的止血有效率明显高于A、C组,差异有统计学意义(P<0.05)。在非静脉上消化道出血治疗上,C组与B组比较差异有统计学意义(P<0.05);A组与B组比较差异无统计学意义(P>0.05)。在静脉性上消化道出血治疗上,B组与A、C组比较差异均有统计学意义(P<0.05)。结论内镜联合奥曲肽治疗上消化道出血的效果显著。

Objective To investigate the clinical effect of upper gastrointestinal bleeding by octreotide combination with endoscopic therapy.Methods From March 2010 to June 2014,our hospital has 94 patients with diagnosis of upper gastrointestinal bleeding,which were randomly divided into 3groups(A,B,C).26 patients of A group were treated by endoscopic therapy;endoscopic therapy combination with octreotide was used in 45 cases in group B;group C(23 patients)were treated with octreotide alone.Comparing the efficiency during the three groups after 72 h.Results The efficiency of upper gastrointestinal bleeding by octreotide combination with endoscopic therapy was more higher than that of the other two groups,in non-variceal upper GI bleeding,the efficiency by octreotide combination with endoscopic therapy was significantly greater than octreotide(P<0.05),but the efficiency by octreotide combination with endoscopic therapy had no obvious difference than endoscopic therapy(P>0.05).In variceal upper GI bleeding,he efficiency by octreotide combination with endoscopic therapy was significantly greater than the other two groups(P<0.05).Conclusion Endoscopy combination with octreotide in the treatment of upper gastrointestinal bleeding is effective.