可降解锌基生物材料的研究进展

Research Progress on Biodegradable Zinc-Based Biomaterials

Zn作为人体必需的微量元素,具有理论适中的降解速率和降解行为,因此在近年来,成为继镁合金与铁合金后的一种新的可降解医用植入材料。锌合金的设计、加工制备以及降解机理的研究刚处于起步阶段,尚未形成系统性的研究成果。本文就目前可降解锌合金的研究现状及未来的研究方向进行综述。

In recent years, zinc, as an essential trace element, with its alloys has attracted increasing attention as new biodegradable metals because of its appropriate degradation rate and degradation behavior. In this stage, it appears that the fabrication and degradation mechanism of zinc alloys as biodegradable metal still needs abundant systematic study. This review summarizes progress towards biodegradable zinc alloys. It emphasizes the current understanding of physiological and biological benefits of zinc and its biocompatibility. Finally, the review provides an outlook on challenges in designing zincbased stents of optimal mechanical properties and biodegradation rate.