超声内镜引导下无水乙醇消融治疗胰腺囊性肿瘤的疗效分析

Therapeutic value of EUS-guided dehydrated ethanol lavage for pancreatic cystic neoplasms

目的评价超声内镜（EUS）引导下无水乙醇消融治疗胰腺囊性肿瘤的有效性和安全性。方法收集2014年4月至2016年12月因胰腺囊性肿瘤在南京鼓楼医院行EUS引导下无水乙醇消融治疗的15侧患者资料。患者术前均接受EUS引导下细针穿刺术。回顾性分析EUS引导下无水乙醇消融治疗的临床疗效及不良事件发生情况。结果15例患者每人均行1次无水乙醇消融术，手术均成功，术中及术后均无并发症出现。随访时间3～30个月，中位随访时间15个月，12例患者完成长期随访，其中病灶完全缓解6例，部分缓解6例，无患者行外科手术。结论无水乙醇消融治疗胰腺囊性肿瘤是一种安全可行的治疗方式。

Objective To evaluate the safety and feasibility of endoscopic uhrasonography （EUS）- guided dehydrated ethanol lavage on treatment of pancreatic cystic neoplasms （PCN）. Methods The data of 15 patients with PCN treated by EUS-guided dehydrated ethanol lavage in Nanjing Drum Tower Hospital from April 2014 to December 2016 were retrospectively analyzed. All the patients underwent EUS-guided fine needle aspiration, and then the cyst cavity was lavaged with dehydrated ethanol. The curative effects and complications were evaluated after the procedure. Results Each patient had one operation and all the operations were successful. No operation-related intraoperative or postoperative complications occurred. Patients were followed up for a median time of 15 months （range from 3-30 months）. Twelve patients finished a long term follow-up, including 6 cases of complete remission and 6 cases of partly remission. None of the patients underwent surgical resection. Conclusion Dehydrated ethanol lavage is safe and feasible for treatment of PCN.