磁共振波谱分析中胆碱对四肢软组织肿瘤的诊断价值

The Value of Magnetic Resonance Spectroscopy(~1H-MRS) in the Soft Tissue Tumors of the Extremities

目的:探讨磁共振波谱(1H-MRS)分析中胆碱对四肢软组织肿瘤的诊断价值。方法:回顾性分析82例经病理证实,四肢软组织实性病变的肿瘤患者资料,其中良性肿瘤39例,恶性肿瘤43例,病理诊断前均行常规磁共振(MRI)及1H-MRS检查,分别记录肿瘤区域代谢产物胆碱(Cho)、肌酸(Cr)的峰值积分,并计算出Cho与Cr的峰值积分比值(Cho/Cr)。结果:恶性肿瘤Cho、Cr及Cho/Cr平均值分别为20.52±8.42、6.33±3.26、3.25±1.45,良性肿瘤Cho、Cr及Cho/Cr平均值分别为9.36±4.63、6.25±3.03、1.50±0.31,恶性肿瘤较良性肿瘤Cho、Cho/Cr明显增高,具有统计学差异(P<0.05),两者的Cr值无明显统计学差异(P>0.05)。结论:1H-MRS分析Cho及Cho/Cr对四肢软组织肿瘤良恶性的定性具有重要价值。

Objective： To evaluate the value of magnetic resonance spectroscopy （IH-MRS） in the soft tissue tumors of the extremities. Methods： A retrospective analysis of 82 cases confirmed by pathology was conducted, of them, 39 patients were benign tum0rs, 43 were malignant tumors. Magnetic resonance imaging （MRI） and ^1H-MRS were performed before pathology diagnosis. Record the peak value of choline （Cho） ,creatine （Cr）and Cho/Cr. Results：The mean of Cho,Cr,Cho/Cr of the malignant tumom are separately 20.52 ± 8.42,6.33 ± 3.26,3.25 ± 1.45 ;the mean of Cho,Cr, Cho/Cr of the benign tumors are separately 9.36 ± 4.63,6.25 ＋ 3.03,1.50 ± 0.31 . There is significant difference between benign and malignant soft tissue tumors of Cho,Cho/Cr（P 〈0.05）, There is no significant difference between benign and malignant soft tissue tumors of Cr（ P 〉 0.05 ）. Condusion： Cho and Cho/Cr of 1 H-MRS have important value in the quali- tative analysis of benign and malignant soft tissue tumors.