催化异氰酸酯基与羟基反应选择性的研究进展

The Selectivity of Catalysts for the Reaction of Isocyanate and Hydroxyl Groups

在异氰酸酯基与羟基的反应中使用催化剂是必不可少的,它不仅能够提升反应效率,还可表现出选择性以满足不同的合成需求。从催化剂对不对称异氰酸酯两个不同反应活性的异氰酸酯基的选择性,以及对不同的带活泼氢亲核试剂的选择性的角度,综述了近年来有关催化剂催化异氰酸酯基与羟基反应的选择性的研究进展。

The use of catalysts is indispensable for the reaction between isocyanate and hydroxyl groups. The catalysts can not only promote the reaction rate, but also demonstrate the quality of selectiveness which can be requisite under certain synthetic circumstances. Regarding two aspects, this review covered recent advances in the selectivity of catalysts for the reaction of isocyanate and hydroxyl groups. One aspect was the catalysts＇ selectivity upon the asymmetrical diisocyanates＇ two isocaynate group with different reactivity, and the other was the catalysts＇ selectivity of isocyanatc reacting with different nucleophilic reactants with active hydrogen.