卡络磺钠联合护理干预治疗鼾症64例临床研究

Clinical Study of Carbazochrome Sodium Sulfonate Combined with Nursing Intervention for Treating Sleep Apnea Syndrome in 64 Cases

目的探讨卡络磺钠联合护理干预治疗鼾症的临床疗效。方法选择2016年3月至2017年3月医院拟行悬雍垂腭咽成形术的鼾症患儿128例,按随机数字表法分成两组,各64例。在常规检查基础上,对照组仅予0.9%氯化钠注射液100 m L,观察组予卡络磺钠注射液,均静脉滴注,两组患儿均给予手术室舒适护理干预。记录两组患儿术中出血量、术后渗血量、插管拔出时间及二次手术率。结果观察组患儿术中出血量和术后渗血量显著低于对照组,插管拔出时间显著短于对照组,且二次手术率(1.56%)显著低于对照组(10.94%,P<0.05);观察组呼吸暂停低通气指数显著低于对照组,氧饱和度(SaO_2)、全夜最低SaO_2显著高于对照组(P<0.05)。结论卡络磺钠静脉滴注用于手术治疗鼾症的疗效明显,静脉滴注过程中加强手术室护理干预是保证良好疗效的有效措施,值得临床推广。

Objective To investigate the clinical effect of carbazochrome sodium sulfonate combined with nursing intervention for treating sleep apnea syndrome （ SAS ） . Methods Totally 128 children patients with SAS arranged to receive uvulopalato pharyngoplasty （ UPPP ） from March 2016 to March 2017 in our hospital were divided into two groups according to the random number table method, 64 cases in each group. On the basis of conventional treatment, the control group was given 0. 9% Sodium Chloride Injection 100 mL, while the observation group was given Carbazochrome Sodium Sulfonate Injection. The two groups were given operation room comfortable nursing intervention. The intraoperative blood loss, postoperative bleeding volume, time of extracting intubation and the second operation rate of the two groups were recorded. Results The intraoperative blood loss and postoperative bleeding volume of the observation group were significantly lower than those of the control group, and the time of extracting intubation was significantly shorter than that of the control group, the second operation rate of the observation group was 1. 56%, which was significantly lower than 10. 94% of the control group （ P 〈 0. 05 ） . The apnea hypopnea index （ AHI ） of the observation group was significantly lower than that of the control group, and the SaO2, the minimun SaO2 in the whole night of the observation group were significantly higher than those of the control group （ P 〈 0. 05 ） . Conclusion The effect of intravenous drip of carbazochrome sodium sulfonate in treatment of patients with SAS is obvious, in the process of intravenous drip, strengthening the nursing intervention in operation room is an effective measure to ensure good curative effect, which is worthy of clinical promotion.