动态心电图对参松养心胶囊与美托洛尔联合治疗房性心律失常的疗效观察

Effectiveness of combined treatment of shensongyangxin capsule and metoprolol on atrial arrhythmia by ambulatory electrocardiography

目的通过动态心电图观察参松养心胶囊与美托洛尔联合治疗心律失常的疗效。方法随机将78例频发房性早搏、短阵房性心动过速患者分为两组,每组39例。A组(参松养心胶囊+美托洛尔):口服参松养心胶囊4粒/次,3次/d,同时给予美托洛尔(12.5~25)mg/次,2次/d;B组:口服美托洛尔(12.5~25)mg/次,2次/d。治疗4周后,分别观察两组动态心电图的变化情况,并进行比较。结果 A组心律失常改善率为97.44%,B组改善率为64.10%,差异有统计学意义(P<0.05)。结论通过动态心电图可更清晰地观察到,参松养心胶囊与美托洛尔联合治疗频发房性早搏及短阵房速的效果明显优于单用美托洛尔。

Objective To observe and evaluate the effectiveness of the combined treatment of shensongyangxin capsule and metoprolol on atrial arrhythmia by ambulatory electrocardiography （AECG） . Methods Seventy-eight patients with frequent atrial premature beats and paroxysmal at-rial tachycardia were randomly divided into two groups, each with 39 cases. Patients in group A un-derwent a combined therapy of shensongyangxin capsule and metoprolol. They orally took 4 shens-ongyangxin capsules per time, 3 times per day and metoprolol at a dose of 12. 5 - 25 mg per time, 2 times per day. Patients in group B orally took metoprolol at a dose of 12. 5 - 25 mg per time, 2 times per day. After 4 weeks of treatment, AECG changes of the two groups were observed and compared.Results The improvement rate of arrhythmia in group A and B was 97.4 4 % and 64. 10% , respec-tively ,with statistically significant difference （ P 〈 0. 05）. Conclusion It is obviously observed by AECG that the combined treatment of shensongyangxin capsule and metoprolol significantly strength-ens the curative effect on frequent atrial premature beats and paroxysmal atrial tachycardia if compared with metoprolol alone.