“房颤一站式治疗”的方法学与疗效评估

The methodology and efficacy evaluation of “one-stop treatment of atrial fibrillation”

心房颤动简称"房颤",是目前临床最受关注且循证医学进展最为迅速的心律失常之一。除抗凝、心室率控制等治疗手段外,从症状控制角度而言,导管消融(包括射频、冷冻等能量来源)是目前指南推荐的首选治疗方法,但其尚未能作为有效的心源性卒中预防手段而得到认可;而经皮左心耳封堵技术则弥补了该空白,成为卒中高危、不能耐受长期抗凝的房颤患者更好的选择之一。由此而衍生的"房颤一站式治疗"也成为当前业界的热门话题之一。本文就"房颤一站式治疗"的方法学及疗效进展进行讨论。

Atiial fibiillation（AF） as one kind of arrhythmias has gained the most attention clinically and the greatest progress in evidence-based medicine at present. Besides the therapies such as anticoagulant therapy and ventricular rate control, catheter ablation （energy sources including radiofrequency and freezing） is the first choice of treatment recommended by guidelines at present from the perspective of synptom con-trol. However, its effectiveness in preventing against cardiac apoplexy has not been authorized yet. The technique of percutaneous left atrial appendage occlusion fills the blank and becomes one of the better choices for AF patients who are high-risky of stroke and intolerance of permanent anticoagulant therapy. The derivative u one-stop treatment of AF＂ thereof has become one of hot topics of current industry. This paper discusses the methodology of the uone-stop treatment of AF＂ and advances of its curative effect.