瑞芬太尼诱导用于产科全麻对产妇及新生儿的影响

The impact of remifentanil induced general anesthesia on the maternals and neonatals

目的:探讨瑞芬太尼用于产科全身麻醉(简称全麻)诱导对产妇及新生儿的影响.方法:选择行剖宫产手术并且必须行全麻的产妇70例,随机分为A组(对照组)和B组(瑞芬太尼诱导组).监测患者入室(T0)、切皮(T1)、气管插管(T2)和拔管(T3)4个时间点两组产妇血流动力学参数、所有新生儿出生时Apgar评分.结果:切皮、插管两个时间点,A组患者血压、心率明显高于B组患者,拔管时两组患者血压、心率比较无统计学差异.两组新生儿Apgar评分无统计学差异.结论:瑞芬太尼麻醉诱导平稳,且对新生儿Apgar评分无影响,因此,瑞芬太尼可以安全地用于产科全麻诱导.

Aim： To investigate the impact of remifentanil on the pregnant women and the new borns when remifentanil is used in the pregnant women undergoing general anesthesia Methods： Seventy hospitalized patients who must undergo general anesthesia were included in this study. The patients were randomized into 2 groups： Group A（ Control group） and group B（ Remifentanil group）. Hemodynamic changes at different time points were recorded for all patients： getting into the operation room（ T0）,skin incision（ T1）,intubation（ T2） and extubation（ T3）,and Apgar scores for all the new borns. Results： At the time point T0 and during extubation, the patients showed no significant differences in the hemodynamic parameters. During skin incision and intubation, the values of the heart rate（ HR）,systolic blood pressure（ SBP） and diastolic blood pressure（ DBP） in group A were significantly higher than those in group B（ P 0. 05）,but there were no significant differences in Apgar scores among all the new borns. Conclusion： The cesarean section induced by remifentanil is more stable and has nosignificant impacts on the new born babies,suggesting that remifentanil can be safely used in cesarean section.