肠易激综合征各亚型患者的生活方式分析

Analysis of lifestyle in patients with various subtype irritable bowel syndrome

目的:探讨罗马Ⅲ标准诊断分类的肠易激综合征(IBS)4个亚型间的生活方式。方法:选取就诊的IBS患者,根据罗马Ⅲ标准分为腹泻型肠易激综合征(IBS-D)组58例、便秘性肠易激综合征(IBS-C)组43例、交替型肠易激综合征(IBS-M)组20例、不定型肠易激综合征(IBS-U)组18例,选取相同例数健康查体者139例作为对照组。依据IBS诊断要点及相关生活方式自行设计问卷调查表分别对各组近6个月内生活方式进行调查,分析对比各组间差异。结果:4个亚型IBS组在进食蔬菜和水果频率、每日睡眠时间、每周睡眠障碍频率较对照组差异均有统计学意义(P<0.01);IBS-D组在进食辛辣、冷食频率较其余3个亚型及对照组差异有统计学意义(P<0.01);合理进食蔬菜和水果、适当的睡眠时间及良好的早餐习惯为IBS患病的保护因素,差异有统计学意义(P<0.05),而睡眠障碍频率高、吸烟为IBS患者的危险因素,差异有统计学意义(P<0.05)。结论:在临床上为不同亚型IBS患者提供正确的生活方式指导对IBS症状控制有一定意义。

Objective To analyze lifestyle in patients with 4 subtypes of irritable bowel syndrome（ IBS） diagnosed according to RomanⅢ criterea. Method Patients diagnosed with irritable bowel syndrome were analyzed retrospectively,of which 58 patients with diarrheal irritable bowel syndrome（ IBS-D）,43 patients with constipation-predominant irritable bowel syndrome（ IBS-C）,20 patients with mixed irritable bowel syndrome（ IBS-M） and 18 patients with unstable irritable bowel syndrome（ IBS-U） respectively served as the observation group,and 139 normal people were selected as the control group. All the patients received the questionnaires designed by Rome Ⅲ diagnostic criteria to study the lifestyles related to IBS in last six months. Results The differences between IBS and control group in requency of eating fruits and vegetables,daily sleep hours,frequency of weekly sleep disorder among were statistically significant（ P〈 0. 01）. The differences between IBS-D and the other groubs in eating cold and spicy food were statistically significant（ P〈 0. 01）. The protective factors of IBS included eating breakfast,fruits and vegetables and appropriate sleep time（ P〈 0. 05）. Smoking and high frequency of weekly sleep disorders are the risk factor of IBS（ P〈 0. 05）. Conclusion A proper clinic guidance to different subtypes of IBS are helpful for preventing the symptoms of IBS.