新生儿低血糖症70例临床分析

Clinical analysis of 70cases of neonatal hypoglycemia

目的:探究新生儿低血糖症的临床表现特点、致病危险因素及临床治疗情况。方法:选择本院2014年1月至2017年5月收治的70例新生儿低血糖症患儿,回顾性分析70例患儿临床症状表现、致病因素及治疗和预后效果。结果:70例患儿中有32例患儿表现出异常症状,占比为45.71%,主要表现有刺激反应能力低下、烦躁不安、四肢震颤、发绀等;对70例患儿的病因分析显示,致病危险因素主要为早产儿、低出生体质量、孕母体糖尿病、喂养不当、感染、窒息等;70例患儿经连续72小时干预治疗后,血糖水平及临床症状均得到改善,治疗后血糖水平为(3.85±0.51)mmol/L,血清胰岛素水平为(9.27±0.22)μU/mL,血糖水平显著高于出生时(P<0.05),胰岛素水平显著低于治疗前(P<0.05),所有患儿均痊愈出院。结论:新生儿低血糖症的危险因素多样复杂,孕产妇在妊娠期要定期产检、合理饮食,对合并有低血糖症高危因素的新生儿要加强血糖和胰岛素水平监测,密切观察患儿的临床症状表现,及早发现及时纠正,以避免低血糖状态下对患儿神经及脑损伤,提高新生儿生存质量。

Objective：To investigate the clinical characteristics,risk factors and clinical treatment of neonatal hypoglycemia.Methods：We selected 70 cases of neonatal hypoglycemia in our hospital from January 2014 to May 2017.The clinical symptoms,pathogenic factors,treatment and prognosis of 70 cases of children with hypoglycemia were analyzed retrospectively.Results：In 70 cases,32 cases showed abnormal symptoms,accounted for 45.71%,mainly a stimulus response ability is low,irritability,tremor,cyanosis;etiological analysis of 70 cases showed that the main risk factors for preterm birth,low birth weight,gestational diabetes,maternal improper feeding,infection,asphyxia;70 cases were diagnosed by continuous 72 hafter treatment,blood glucose level and clinical symptoms were improved after treatment,the blood glucose level（3.85±0.51）mmol/L,serum insulin level（9.27±0.22）μU/mL,the blood glucose level was significantly higher than at birth（P〈0.05）,insulin level was significantly lower than that of before treatment（P〈0.05）,all patients were cured.Conclusion：The risk factors of neonatal hypoglycemia complicated,pregnant women during pregnancy to regular prenatal examination,reasonable diet,there are high risk factors of neonatal hypoglycemia should strengthen the monitoring of blood glucose and insulin levels with close observation of clinical symptoms in children,and the correct in time,in order to avoid damage to the nerve and brain of patients with hypoglycemia next,improve the quality of life.