脑出血不同预后患者入院血脂水平与NIHSS评分回顾性分析

Retrospective analysis of blood lipid levels and NIHSS score of patients with different prognosis after intracerebral hemorrhage

目的回顾性分析脑出血不同预后患者入院血脂水平与NIHSS评分情况,探讨脑出血患者血脂水平与NIHSS评分对其预后的影响。方法选取86例脑出血不同预后患者为对象,根据患者不同预后情况,将86例患者分为预后良好组(57例)和预后不良组(29例),分别对各组患者入院时TC、TG、HDL-C及LDL-C等血脂指标以及NIHSS评分进行比较,分析患者入院血脂指标及NIHSS评分与预后的相关性。结果治疗4周后,预后良好组57例治愈;预后不良组11例出现偏瘫,8例出现失语,6例昏迷不醒,4例死亡。预后良好组入院TC、TG、LDL-C指标及NIHSS评分均明显低于预后不良组,HDL-C指标水平均明显高于预后不良组(P<0.05)。患者TG、LDL-C水平及NIHSS评分与患者预后呈负相关性(P<0.05)。HDL-C与患者预后良好呈正相关(P<0.05)。结论脑血管患者入院血脂水平异常及NIHSS评分的高低可能是反映患者预后不良的重要因素。

Objective To retrospectively analyze the blood lipid level and NIHSS score of patients with different prognosis of cerebral hemorrhage,and investigate the influence of blood lipid level and NIHSS score on prognosis. Methods Eighty-six cases of cerebral hemorrhage clinical data of patients with different prognosis was selected as the object,according to the different prognosis of patients,86 patients were divided into good prognosis group （57 cases） and poor prognosis group （29 cases）,and 30 healthy subjects were selected as control group,respectively. The TC,TG,H-DLC and L-DLC,the blood lipid index and NIHSS score of each group of patients were compared. Results After 4 weeks of treatment,57 cases of good prognosis group were cured; among the poor prognosis group,11 cases had hemiplegia,8 cases had aphasia,6 cases were aggravated and 4 cases died. The levels of TC,LDL-C and NIHSS of patients in good prognosis group were significantly lower than those in poor prognosis group,HDL-C level was significantly higher than that of the poor group （P 〈0. 05）. There was a negative correlation between TG,LDL-C and NIHSS scores in patients with cerebral hemorrhage （P 〈0. 05）. There was a positive correlation between HDL-C and cerebral hemorrhage （P 〈0. 05）. Conclusion The abnormal blood lipid levels and the NIHSS score of patients with cerebrovascular diseases may be the important factors for the poor prognosis of patients.