^(18)F-FDG符合线路正电子成像在肺部良恶性肿瘤鉴别中的应用

Evaluation of ^(18)F-FDG imaging with coincidence SPECT in lung benign and malignant tumor

目的探讨18氟-脱氧葡萄糖符合线路正电子成像(18 F-FDG SPECT/CT)在肺部良恶性肿瘤鉴别中的应用。方法选取2013年1月至2015年12月间我院行18F-FDG SPECT/CT显像后进行外科手术治疗的145例患者的临床资料,将其18F-FDG SPECT/CT显像结果与纤维支气管镜活检或术后病理结果进行对比。结果 18 F-FDG SPECT/CT显像结果与病理结果相符率较高,SPECT/CT肺癌原发灶检出的灵敏度、特异度、阳性预期值、阴性预期值及准确度分别为89.6%(103/115),80.0%(24/30),94.5%(103/109),66.7%(24/36)和87.6%(127/145)。结论18 F-FDG符合线路正电子成像在肺部良恶性肿瘤鉴别中具有较高的临床应用价值,值得临床推广。

Objective To investigate the clinical value in the diagnosis of lung benign and malignant tumor with 18 F-FDG imaging with coincidence SPECT. Methods A total of 145 patients with lung lesions who were found by 18F-FDG SPECT/CT in our hospital were collected from January 2013 to December 2015. The 18F-FDG imaging with coincidence SPECT imaging re- sults and fiberoptic bronchoseopy biopsy or postoperative pathology results were compared. Results 18 F-FDG imaging with coincidence SPECT imaging results and pathological results were uniform with actual values. The sensitivity, specific, positive predictive value, negative predictive value and accuracy of coincidence SPECT with 18 F-FDG examination was 89.6 %, 80.0%, 94.5 %, 66.7%, and 87.6%, respectively. Conclusion The 18 F-FDG imaging with coincidence SPECT has high value in the diagnosis of lung benign and malignant tumor and worthy of clinical promotion.