胎儿心脏畸形筛查中五横切面检查法的应用效果研究

The clinical value of fetal five transverse section for rapid screening of fetal cardiac malformation

目的分析五横切面检查法在胎儿心脏畸形产前筛查中的应用效果。方法从2012年7月-2015年7月我院收治的产前常规检查孕妇中,抽取5500例采用五横切面筛查法的产妇作为研究对象。比较五横切面检查结果和产后或尸检确诊结果,并计算五横切面筛查的准确性。结果在5500例孕妇中,五横切面筛查检出胎儿心脏畸形34例,检出率为0.62%。其中17例孕妇正常妊娠、16例引产、1例胎儿死亡,经产后或尸检确诊。胎儿经产后或尸检确诊显示,五横切面筛查漏诊4例、误诊3例。计算可知阴性预测值为5469/5473=99.9%,阳性预测值为31/34=91.2%,特异性为5469/5472=99.9%,敏感性为31/35=88.6%。结论产前常规检查时,五横切面检查法在胎儿心脏畸形筛查中的准确性高,推荐临床应用。

Objective To analyze the effect of five transverse section examination in prenatal screening of fetal cardiac malformation.Methods from July 2012 to-2015 in July in our hospital for prenatal routine examination of pregnant women,5500 cases of the use of the transverse section of the screening method of maternal as the research object of the five.The results were compared with the results of five transverse sections and the results of postpartum or autopsy,and the accuracy of the five transverse section was calculated.Results In 5500 cases of pregnant women,there were five cases of fetal cardiac malformations in the transverse section of the 34 cases,the detection rate was 0.62%.Of which 17 cases of normal pregnant women,16 cases of abortion,1 cases of fetal death,or autopsy confirmed by.The fetus or autopsy confirmed by display,five cross-sectional screening 4 cases of misdiagnosis,misdiagnosis in 3 cases.The negative predictive value was 5469/5473=99.9%,the positive predictive value was 31/34=91.2%,the specificity was5469/5472=99.9%,and the sensitivity was 31/35=88.6%.Conclusion The accuracy of five transverse section examination in the prenatal screening of fetal heart defects is high.