摘要
采用电化学沉积的方法制备了氧化锆修饰玻碳电极,并用于抗癌药物甲氨蝶呤的循环伏安法测定。在优化的实验条件下,甲氨蝶呤的氧化峰电流与其浓度在5.5×10^(-7)~3.7×10^(-4)mol/L范围内呈良好的线性关系,线性回归方程Ip(μA)=1.021+0.05008CMTX,相关系数r=0.9981。该方法具有方法简单、快速、环境友好等优点。
Zirconium oxide modified glassy carbon electrode was prepared by electrodeposition method, and used for the determination of methotrexate （MTX） by cyclic voltammetry. Under the conditions for optimization, the peak current of MTX is linear relationship with its concentration in the range of 5.5 × 10-7 - 1.2× 10 -4 mol/L The linear regression equation is Ip（A）=1.021-0.05008 C MTX with a correlation coefficient of 0.9981. The method has advantage of simple, fast, environmentally friendly and so on.
作者
黄德乾
武海
宋崇富
盛良全
张宏
刘昭第
徐华杰
李坤友
王鹏
Huang Deqian Wu Hai Song Chongfu Sheng Liangquan Zhang Hong Liu Zhaodi Xu Huajie Li Kunyou Wang Peng(School of Chemistry and Materials Engineering, Fuyang Normal University, Fuyang 236041 Anhui Provincial Key Laboratory for Degradation and Monitoring of Pollution of The Environment, Fuyang 236037, China)
出处
《广东化工》
CAS
2017年第20期221-223,共3页
Guangdong Chemical Industry
基金
安徽高校省级科学研究项目(2014KJ024)
南京大学"生命分析化学国家重点实验室"开放课题(SKLACLS1712)
阜阳师范学院现代分析技术创新团队(kytd201701)
关键词
甲氨蝶呤
氧化锆
修饰电极
测定
methotrexalc
zirconium oxide
modified electrode
determination
