海南州育龄妇女TORCH感染调查

TORCH infections among women of childbearing age from Hainan prefecture of Qinghai province

目的了解青海省海南州育龄妇女TORCH的感染情况,探讨不同因素与TORCH感染的关系。方法收集青海省海南州3县194名育龄妇女的血清标本,采用酶联免疫吸附试验(ELISA)检测TORCH各病原体感染的相关抗体IgM与IgG。对研究对象进行问卷调查,统计TORCH的感染情况。结果 194例育龄妇女TORCH(TOX、RV、CMV、HSV-Ⅰ及HSV-Ⅱ)IgM阳性率,分别为7.22%、10.82%、5.15%、2.58%、0.52%;IgG阳性率分别为5.15%、67.01%、75.26%、83.52%、6.70%;TORCH的IgM和IgG同时检测的结果:IgM(+)IgG(+):RV例数最多为19例,IgM(-)IgG(+):HSV-Ⅰ例数最多为157例,IgM(+)IgG(-):TOX例数最多为14例,lg M(-)IgG(-):HSV-Ⅱ例数最多为180例。职业分布上,HSV-Ⅰ的IgM阳性率有差异,以学生最高,为12.50%;年龄分布上,HSV-Ⅰ的IgM阳性率以20岁以下最高,为16.67%;HSV-Ⅰ的IgM阳性率在无孕育史的妇女中明显高于有孕育史的妇女(χ2=13.86,P<0.05);IgM和IgG阳性率在不同县、民族、文化程度及有否妇科疾病均无差异(P>0.05)。结论海南州育龄妇女TORCH的阳性率比较高,尤其是HSV-Ⅰ的感染较为明显,当地相关部门应该加强健康教育,并做好早期筛查,以提高人口素质。

Objective To study TORCH infections in women of childbearing ageof Hainan prefecture of Qinghai province. Methods 194 serum specimens from women of childbearing age were collected of 3 counties in Hainan prefecture in Qinghai province and tested by enzyme-linked immunosorbent assay （ELISA） for IgM and IgG of TORCH infections, data were analyzed statistically.Results The results showed that IgM positive rates of TORCH （ TOX, RV, CMV, HSV I and II） were 7.22%, 10.82 %, 5.15 %, 2.58 % and 0.52 % respectively. IgG positive rates of TORCH were 5.15 %, 67.01%, 75.26 %, 83.52 %, 6.70 %. Both IgM and IgG of TORCH screening results showed that 19 RV cases were IgM（＋） IgG （＋）, HSV- I had more cases for IgM （-） and IgG （＋） which was 157, TOX had more cases for IgM（＋） and IgG （-） which was 14, HSV- II had more cases for concurrent IgM （-） and IgG （-） which was 180. Among all occupations, students had highest HSV- I IgM rates which were 12.50 %. As for age distribution, highest IgM of HSV- I was found in cases under 20 years which was 16.67 %. As for birth history, women of no birth HSV- I IgM rate was significantly higher than had birth history if2= 13.86, P〈0.05）. IgM and IgG positive rates had no statistical significance in regions, ethnic groups, education and gynecological diseases （P〉 0. 05）. Conclusion TORCH infection is relatively high in women of childbearing age in Hainan prefecture, especially HSV- I. Local authorities should strengthen health education and carry out early screening so as to improve the quality of the population.